2. Signaling Pathways
  3. Epigenetics
  4. Histone Methyltransferase
  5. SUV39H2/KMT1B Isoform

SUV39H2/KMT1B

 

SUV39H2/KMT1B Related Products (1):

Cat. No. Product Name Effect Purity
  • HY-122182
    OTS193320
    		Inhibitor 98.64%
    OTS193320, a imidazo[1,2-a]pyridine compound, is a SUV39H2 methyltransferase activity inhibitor. OTS193320 decreases global histone H3 lysine 9 tri-methylation levels in breast cancer cells and triggers apoptotic cell death. Combination of OTS193320 with Doxorubicin (DOX; HY-15142A) results in reduction of γ-H2AX levels as well as cancer cell viability compared to a single agent OTS193320 or DOX.